The 19-year-old grandson of team owner Joe Gibbs from Charlotte, North Carolina, will be substituting for Kurt Busch for a third consecutive Cup Series weekend at the Irish Hills.
The 27-year-old native from Norman, Oklahoma, became the 14th different competitor to secure a spot for the 2022 Cup Series Playoffs by winning at the Magic Mile.
The 2018 Cup Series champion led 20 of 242 over-scheduled laps and prevailed in a late crossover battle with Kyle Busch to capture the inaugural Cup event in Madison, Illinois.
Kurt Busch, the 2004 Cup Series champion from Las Vegas, Nevada, led a race-high 116 of 267 to notch his first victory in the Heartland State and his first driving for 23XI Racing.
Running in the top-10 before both cars were taken out in a massive lap 262 crash during Sunday's Goodyear 400 at Darlington seemed par for the course for the 23XI Racing Toyotas of Kurt Busch and Bubba Wallace.
The 29-year-old Chastain from Alva, Florida, rallied from an early pit road speeding penalty to overtake Erik Jones on the final lap through the tri-oval to claim his second career win in NASCAR's premier series.
The 24-year-old Byron from Charlotte, North Carolina, led a race-high 212 of 403 and fended off Joey Logano during an overtime shootout to repeat as a Cup winner at the Paperclip-shaped short track.
