The 22-year-old Smith from Huntington Beach, California, will be filling in for Buescher, who will not compete at Gateway following a positive COVID-19 test.
The 41-year-old Hamlin from Chesterfield, Virginia, led four times for 15 of 413 over-scheduled laps and outlasted the on-track chaos and two overtime attempts to notch his first 600 triumph at the Queen City.
Stenhouse, Buescher and Suarez claimed respective stage victories while Erik Jones claimed the Fan Vote title to transfer from the All-Star Open to All-Star Race.
The 2020 NASCAR Xfinity Series champion commenced his first full-time campaign in the Cup Series by becoming the 41st different winner of the Great American Race.
The 2015 Xfinity Series champion capped off a perfect day for the newly named Roush Fenway Keselowski Racing by winning the second of two Duel events at Daytona.
The Mobile, Alabama, native fended off the field in the closing laps of the second stage to become the second African-American competitor to win in NASCAR's premier series.
The High Point, North Carolina, native claimed his third victory of the season and his second consecutive in recent weeks at the world center of racing.